Mesenchymal stem cells induce T-cell tolerance and protect the preterm brain after global hypoxia-ischemia.

Mesenchymal stem cells induce T-cell tolerance and protect the preterm brain after global hypoxia-ischemia.

Hypoxic-ischemic encephalopathy (HIE) in preterm infants is a severe disease for which no curative treatment is available. Cerebral inflammation and invasion of activated peripheral immune cells have been shown to play a pivotal role in the etiology of white matter injury, which is the clinical hall...

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Bibliographic Details
Main Authors: Reint K Jellema, Tim G A M Wolfs, Valéria Lima Passos, Alex Zwanenburg, Daan R M G Ophelders, Elke Kuypers, Anton H N Hopman, Jeroen Dudink, Harry W Steinbusch, Peter Andriessen, Wilfred T V Germeraad, Joris Vanderlocht, Boris W Kramer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3753351?pdf=render

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http://europepmc.org/articles/PMC3753351?pdf=render

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