microRNA-214-3p Suppresses Ankylosing Spondylitis Fibroblast Osteogenesis via BMP–TGFβ Axis and BMP2

microRNA-214-3p Suppresses Ankylosing Spondylitis Fibroblast Osteogenesis via BMP–TGFβ Axis and BMP2

Recent investigations suggest microRNAs (miRs) exert functions in fibroblast osteogenesis in ankylosing spondylitis (AS), an inflammatory rheumatic disease. But the mechanism of miR-214-3p in osteogenic differentiation in AS is not clearly understood yet. In this study, fibroblasts were obtained fro...

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Bibliographic Details
Main Authors: Lixiang Ding, Yukun Yin, Yu Hou, Haoran Jiang, Ji Zhang, Zhong Dai, Genai Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Endocrinology
Subjects:
ankylosing spondylitis
microRNA-214-3p
osteogenic differentiation
bone morphogenic protein 2
BMP–TGFβ signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.609753/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.609753/full

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