The efficacy of etanercept as anti-breast cancer treatment is attenuated by residing macrophages

The efficacy of etanercept as anti-breast cancer treatment is attenuated by residing macrophages

Abstract Background Interaction between microenvironment and breast cancer cells often is not considered at the early stages of drug development leading to failure of many drugs at later clinical stages. Etanercept is a TNF-alpha inhibitor that has been investigated for potential antitumor effect in...

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Bibliographic Details
Main Authors: Elnaz Shirmohammadi, Seyed-Esmaeil Sadat Ebrahimi, Amir Farshchi, Mona Salimi
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Cancer
Subjects:
TNF-α
Etanercept
Breast cancer
Macrophages
Systems biology
Online Access:http://link.springer.com/article/10.1186/s12885-020-07228-y

Internet

http://link.springer.com/article/10.1186/s12885-020-07228-y

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