FK506 biosynthesis is regulated by two positive regulatory elements in <it>Streptomyces tsukubaensis</it>

FK506 biosynthesis is regulated by two positive regulatory elements in <it>Streptomyces tsukubaensis</it>

<p>Abstract</p> <p>Background</p> <p>FK506 (Tacrolimus) is an important immunosuppressant, produced by industrial biosynthetic processes using various <it>Streptomyces</it> species. Considering the complex structure of FK506, it is reasonable to expect compl...

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Bibliographic Details
Main Authors: Goranovič Dušan, Blažič Marko, Magdevska Vasilka, Horvat Jaka, Kuščer Enej, Polak Tomaž, Santos-Aberturas Javier, Martínez-Castro Miriam, Barreiro Carlos, Mrak Peter, Kopitar Gregor, Kosec Gregor, Fujs Štefan, Martín Juan F, Petković Hrvoje
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Microbiology
Subjects:
FK506
Tacrolimus
<it>Streptomyces tsukubaensis</it>
Biosynthesis
Transcriptional regulator
Online Access:http://www.biomedcentral.com/1471-2180/12/238

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http://www.biomedcentral.com/1471-2180/12/238

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