The Identification of the Metabolism Subtypes of Skin Cutaneous Melanoma Associated With the Tumor Microenvironment and the Immunotherapy

The Identification of the Metabolism Subtypes of Skin Cutaneous Melanoma Associated With the Tumor Microenvironment and the Immunotherapy

Skin cutaneous melanoma (SKCM) is a highly aggressive and resistant cancer with immense metabolic heterogeneity. Here, we performed a comprehensive examination of the diverse metabolic signatures of SKCM based on non-negative matrix factorization (NMF) categorization, clustering SKCM into three dist...

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Bibliographic Details
Main Authors: Ronghua Yang, Zhengguang Wang, Jiehua Li, Xiaobing Pi, Runxing Gao, Jun Ma, Yi Qing, Sitong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
metabolism subtypes
tumor microenvironment
skin cutaneous melanoma
immune signature
mutation landscape
immunotherapy response
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.707677/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.707677/full

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