Next-Generation Sequencing for Binary Protein-Protein Interactions

Next-Generation Sequencing for Binary Protein-Protein Interactions

The yeast two-hybrid (Y2H) system exploits host cell genetics in order to display binary protein-protein interactions (PPIs) via defined and selectable phenotypes. Numerous improvements have been made to this method, adapting the screening principle for diverse applications, including drug discovery...

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Bibliographic Details
Main Authors: Bernhard eSuter, Xinmin eZhang, Gustavo ePesce, Andrew eMendelsohn, Savithramma eDinesh-Kumar, Jian-Hua eMao
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Genetics
Subjects:
Next-generation sequencing
protein-protein interactions
yeast two-hybrid
Interactome Mapping
Quantitative Interaction Profiles
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00346/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00346/full

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