Alterations in Cell Mechanics by Actin Cytoskeletal Changes Correlate with Strain-Specific Rubella Virus Phenotypes for Cell Migration and Induction of Apoptosis

Alterations in Cell Mechanics by Actin Cytoskeletal Changes Correlate with Strain-Specific Rubella Virus Phenotypes for Cell Migration and Induction of Apoptosis

The cellular cytoskeleton is central for key cellular functions, and as such is a marker for diseased and infected cell states. Here we analyzed infection with rubella virus (RV) strains with respect to phenotypes in cellular mechanical properties, cell movement, and viral cytopathogenicity. Real-ti...

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Bibliographic Details
Main Authors: Martin Kräter, Jiranuwat Sapudom, Nicole Christin Bilz, Tilo Pompe, Jochen Guck, Claudia Claus
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cells
Subjects:
wound healing
gap closure assay
actin stress fibers
real-time deformability cytometry
cytochalasin D
single cell tracking
cell stiffness
Online Access:http://www.mdpi.com/2073-4409/7/9/136

Internet

http://www.mdpi.com/2073-4409/7/9/136

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