Effects of Acute Confinement Stress-induced Hypothalamic-pituitary Adrenal Axis Activation and Concomitant Peripheral and Central Transforming Growth Factor-β1 Measures in Nonhuman Primates

Transforming growth factor-β1 (TGF-β1) is a multifunctional cytokine with anti-inflammatory, immunosuppressive, and neuroprotective properties. The hypothalamic-pituitary-adrenal axis and immune system exert bidirectional influences on each other, via cortisol and TGF-β1, but the exact nature of the...

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Bibliographic Details
Main Authors: Jeremy D. Coplan, Srinath Gopinath, Chadi G. Abdallah, Jeffrey Margolis, Wei Chen, Bruce A. Scharf, Leonard A. Rosenblum, Olcay A. Batuman, Eric L. P. Smith
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Chronic Stress
Online Access:https://doi.org/10.1177/2470547016688693