Timing of ibuprofen use and musculoskeletal adaptations to exercise training in older adults

Prostaglandins (PGs) increase in bone in response to mechanical loading and stimulate bone formation. Inhibition of cyclooxygenase (COX), the enzyme responsible for PG synthesis, by non-steroidal anti-inflammatory drugs (NSAIDs) impairs the bone formation response to loading in animals when administ...

Full description

Bibliographic Details
Main Authors: Catherine M. Jankowski, Karen Shea, Daniel W. Barry, Sunny A. Linnebur, Pamela Wolfe, John Kittelson, Robert S. Schwartz, Wendy M. Kohrt
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187214000047