Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellin.

Matrix 2 protein ectodomain (M2e) is considered a promising candidate for a broadly protective influenza vaccine. M2e-based vaccines against human influenza A provide only partial protection against avian influenza viruses because of differences in the M2e sequences. In this work, we evaluated the p...

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Main Authors: Liudmila A Stepanova, Roman Y Kotlyarov, Anna A Kovaleva, Marina V Potapchuk, Alexandr V Korotkov, Mariia V Sergeeva, Marina A Kasianenko, Victor V Kuprianov, Nikolai V Ravin, Liudmila M Tsybalova, Konstantin G Skryabin, Oleg I Kiselev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370815?pdf=render