Drug Repurposing: Tolfenamic Acid Inactivates PrbP, a Transcriptional Accessory Protein in Liberibacter asiaticus

Drug Repurposing: Tolfenamic Acid Inactivates PrbP, a Transcriptional Accessory Protein in Liberibacter asiaticus

CLIBASIA_01510, PrbP, is a predicted RNA polymerase binding protein in Liberibacter asiaticus. PrbP was found to regulate expression of a small subset of ribosomal genes through interactions with the β-subunit of the RNA polymerase and a short, specific sequence on the promoter region. Molecular scr...

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Bibliographic Details
Main Authors: Christopher L Gardner, Fernando A Pagliai, Lei Pan, Lora Bojilova, Maria Ines Torino, Graciela L Lorca, Claudio Fabricio Gonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Citrus
antimicrobial
Tolfenamic acid
Liberibacter asiaticus
transcriptional accessory protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01630/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01630/full

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