Deoxyelephantopin induces ROS-mediated autophagy and apoptosis in human colorectal cancer in vitro and in vivo

Objective: To systematically map the stepwise events leading to deoxyelephantopin-induced cell death of HCT116 human colorectal cancer cells and evaluate the effectiveness of deoxyelephantopin in vivo. Methods: HCT116 cells were treated with deoxyelephantopin at various concentrations and time point...

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Bibliographic Details
Main Authors: Chim-Kei Chan, Kind-Leng Tong, Pooi-Fong Wong, Habsah Abdul Kadir
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=3;spage=120;epage=135;aulast=Chan