Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7

It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecu...

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Bibliographic Details
Main Authors: Thomas S. Whittam, Sean D. Reid, Robert K. Selander
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 1998-12-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/4/4/98-0411_article