Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Infection with Helicobacter pylori is responsible for gastritis and gastroduodenal ulcers but is also a high risk factor for the development of gastric adenocarcinoma and lymphoma. The most pathogenic H. pylori strains (i.e., the so-called type I strains) associate the CagA virulence protein with an...

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Bibliographic Details
Main Authors: Amanda Oldani, Mireille Cormont, Veronique Hofman, Valentina Chiozzi, Olivier Oregioni, Alexandra Canonici, Anna Sciullo, Patrizia Sommi, Alessia Fabbri, Vittorio Ricci, Patrice Boquet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19798427/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19798427/?tool=EBI

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