Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure

Heart failure (HF) causes pathological changes in multiple organs, thus affecting the pharmacokinetics (PK) of drugs. The aim of this study was to investigate the PK of candesartan in patients with HF while examining significant covariates and their related impact on estimated clearance using a popu...

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Bibliographic Details
Main Authors: Imad Kassem, Steven Sanche, Jun Li, Guillaume Bonnefois, Marie‐Pierre Dubé, Jean‐Lucien Rouleau, Jean‐Claude Tardif, Michel White, Jacques Turgeon, Fahima Nekka, Simon deDenus
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12842