Monitoring single-cell gene regulation under dynamically controllable conditions with integrated microfluidics and software
How gene regulatory pathways control cell fate decisions in single cells is not fully understood. Here the authors present an integrated dual-input microfluidic chip and a linked analysis software, enabling tracking of gene regulatory responses of single bacterial cells to changing conditions.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-02505-0 |