Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides

Abstract Background The study describes the synthesis, characterization, in vitro antimicrobial and anticancer evaluation of a series of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamide derivatives. The synthesized derivatives were also assessed for in vitro antitubercular activity...

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Bibliographic Details
Main Authors: Snehlata Yadav, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Abhishek Mathur, Balasubramanian Narasimhan
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Chemistry Central Journal
Subjects:
MCF7, HCT116
Isocitrate lyase
Pantothenate synthetase
Resistance
Cytotoxic
In vitro
Online Access:http://link.springer.com/article/10.1186/s13065-018-0432-3

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http://link.springer.com/article/10.1186/s13065-018-0432-3

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