Activation of LXRɑ/β by cholesterol in malignant ascites promotes chemoresistance in ovarian cancer

Abstract Background The purpose of this study was to investigate the role of malignant ascites tumor microenvironment in ovarian cancer progression and chemoresistance. Methods A total of 45 patients with ovarian cancer and three benign ascites were collected at the time of clinical intervention. As...

Full description

Bibliographic Details
Main Authors: Soochi Kim, Maria Lee, Danny N. Dhanasekaran, Yong Sang Song
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-5152-5