<it>Let-7</it> miRNA-binding site polymorphism in the <it>KRAS</it> 3<sup>′</sup>UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/− cetuximab

<it>Let-7</it> miRNA-binding site polymorphism in the <it>KRAS</it> 3<sup>′</sup>UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/− cetuximab

<p>Abstract</p> <p>Background</p> <p>Recent studies have reported associations between a variant allele in a <it>let-7</it> microRNA complementary site (LCS6) within the 3<sup>′</sup>untranslated region (3<sup>′</sup>UTR) of <it>...

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Bibliographic Details
Main Authors: Kjersem Janne B, Ikdahl Tone, Guren Tormod, Skovlund Eva, Sorbye Halfdan, Hamfjord Julian, Pfeiffer Per, Glimelius Bengt, Kersten Christian, Solvang Hiroko, Tveit Kjell M, Kure Elin H
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Cancer
Subjects:
Colorectal cancer
LCS6
MiRNA polymorphism
Cetuximab
Oxaliplatin
5-fluorouracil
Online Access:http://www.biomedcentral.com/1471-2407/12/534

Internet

http://www.biomedcentral.com/1471-2407/12/534

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