3D Cocultures of Osteoblasts and <i>Staphylococcus aureus</i> on Biomimetic Bone Scaffolds as a Tool to Investigate the Host–Pathogen Interface in Osteomyelitis

3D Cocultures of Osteoblasts and <i>Staphylococcus aureus</i> on Biomimetic Bone Scaffolds as a Tool to Investigate the Host–Pathogen Interface in Osteomyelitis

Osteomyelitis (OM) is an infectious disease of the bone primarily caused by the opportunistic pathogen <i>Staphylococcus aureus</i> (SA). This Gram-positive bacterium has evolved a number of strategies to evade the immune response and subvert bone homeostasis, yet the underlying mechanis...

Full description

Bibliographic Details
Main Authors: Raffaella Parente, Valentina Possetti, Maria Lucia Schiavone, Elisabetta Campodoni, Ciro Menale, Mattia Loppini, Andrea Doni, Barbara Bottazzi, Alberto Mantovani, Monica Sandri, Anna Tampieri, Cristina Sobacchi, Antonio Inforzato
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
<i>Staphylococcus aureus</i>
osteomyelitis
osteoblast-like cells
host–pathogen interface
3D models
biomimetic bone scaffolds
Online Access:https://www.mdpi.com/2076-0817/10/7/837

Internet

https://www.mdpi.com/2076-0817/10/7/837

Similar Items