Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

Abstract Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease aggressiveness and clinical outcomes. However, th...

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Bibliographic Details
Main Authors: Vladimir A. Kuznetsov, Zhiqun Tang, Anna V. Ivshina
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Genomics
Subjects:
ovarian cancer
microRNA
prognostic signatures
oncogenic pathway
EMT
neurotrophin signaling
Online Access:http://link.springer.com/article/10.1186/s12864-017-4027-5

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http://link.springer.com/article/10.1186/s12864-017-4027-5

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