Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice

Short-chain fatty acids (SCFA) are important dietary and microbiome metabolites that can have roles in gut immunity as well as further afield. We previously observed that gut microbiome alteration via antibiotics led to attenuated lung inflammatory responses. The rationale for this study was to iden...

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Bibliographic Details
Main Authors: Xiaoli Tian, Judith Hellman, Alexander R. Horswill, Heidi A. Crosby, Kevin P. Francis, Arun Prakash
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
IR
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00159/full