The role of cDC1s in vivo: CD8 T cell priming through cross-presentation [version 1; referees: 3 approved]

The cDC1 subset of classical dendritic cells is specialized for priming CD8 T cell responses through the process of cross-presentation. The molecular mechanisms of cross-presentation remain incompletely understood because of limited biochemical analysis of rare cDC1 cells, difficulty in their geneti...

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Bibliographic Details
Main Authors: Derek Theisen, Kenneth Murphy
Format: Article
Language:English
Published: F1000 Research Ltd 2017-02-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-98/v1