Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

Abstract Given the increasing use of gnotobiotic mouse models for deciphering the effects of human microbial communities on host biology, there is a need to develop new methods for characterizing these animals while maintaining their isolation from environmental microbes. We describe a method for pe...

Full description

Bibliographic Details
Main Authors: Ilia G. Halatchev, David O’Donnell, Matthew C. Hibberd, Jeffrey I. Gordon
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Microbiome
Subjects:
Gnotobiotic mouse husbandry
Host phenotyping
Energy expenditure
Open-circuit indirect calorimetry
Body composition
Obesity
Online Access:https://doi.org/10.1186/s40168-019-0769-4

Internet

https://doi.org/10.1186/s40168-019-0769-4

Similar Items