IL-7 and CD4 T Follicular Helper Cells in HIV-1 Infection

IL-7 was previously shown to upregulate the expression of molecules important for interaction of CD4+ T cells with B cells. It is poorly studied whether IL-7 has a role in the biology of T follicular helper (Tfh) cells and whether IL-7 dysregulates the expression of B-cell costimulatory molecules on...

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Bibliographic Details
Main Authors: Francesca Chiodi, Yonas Bekele, Rebecka Lantto Graham, Aikaterini Nasi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00451/full