Comparing ESC and iPSC—Based Models for Human Genetic Disorders

Traditionally, human disorders were studied using animal models or somatic cells taken from patients. Such studies enabled the analysis of the molecular mechanisms of numerous disorders, and led to the discovery of new treatments. Yet, these systems are limited or even irrelevant in modeling multi...

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Bibliographic Details
Main Authors: Tomer Halevy, Achia Urbach
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/3/4/1146