Fully automated sequence alignment methods are comparable to, and much faster than, traditional methods in large data sets: an example with hepatitis B virus

Fully automated sequence alignment methods are comparable to, and much faster than, traditional methods in large data sets: an example with hepatitis B virus

Aligning sequences for phylogenetic analysis (multiple sequence alignment; MSA) is an important, but increasingly computationally expensive step with the recent surge in DNA sequence data. Much of this sequence data is publicly available, but can be extremely fragmentary (i.e., a combination of full...

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Bibliographic Details
Main Authors: Therese A. Catanach, Andrew D. Sweet, Nam-phuong D. Nguyen, Rhiannon M. Peery, Andrew H. Debevec, Andrea K. Thomer, Amanda C. Owings, Bret M. Boyd, Aron D. Katz, Felipe N. Soto-Adames, Julie M. Allen
Format: Article
Language:English
Published: PeerJ Inc. 2019-01-01
Series:PeerJ
Subjects:
Genome
Automated alignment
Manual alignment
Virus
s-region
HBV
Online Access:https://peerj.com/articles/6142.pdf

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https://peerj.com/articles/6142.pdf

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