Identification of tumor antigens and immune subtypes in lower grade gliomas for mRNA vaccine development

Abstract Background As an important part of tumor immunotherapy for adjunct, therapeutic tumor vaccines have been effective against multiple solid cancers, while their efficacy against lower grade glioma (LGG) remains undefined. Immunophenotyping of tumors is an essential tool to evaluate the immune...

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Bibliographic Details
Main Authors: Liguo Ye, Long Wang, Ji’an Yang, Ping Hu, Chunyu Zhang, Shi’ao Tong, Zhennan Liu, Daofeng Tian
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-03014-x