Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

We have developed a robust, fully automated anti-parasitic drug-screening method that selects compounds specifically targeting parasite enzymes and not their host counterparts, thus allowing the early elimination of compounds with potential side effects. Our yeast system permits multiple parasite ta...

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Bibliographic Details
Main Authors: Elizabeth Bilsland, Andrew Sparkes, Kevin Williams, Harry J. Moss, Michaela de Clare, Pınar Pir, Jem Rowland, Wayne Aubrey, Ron Pateman, Mike Young, Mark Carrington, Ross D. King, Stephen G. Oliver
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
drug screening
parasites
yeast
automation
tropical diseases
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120158

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120158

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