CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina

CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina

The retina is a highly active metabolic organ that displays a particular vulnerability to genetic and environmental factors causing stress and homeostatic imbalance. Mitochondria constitute a bioenergetic hub that coordinates stress response and cellular homeostasis, therefore structural and functio...

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Bibliographic Details
Main Authors: Serena Mirra, Rocío García-Arroyo, Elena B. Domènech, Aleix Gavaldà-Navarro, Carlos Herrera-Úbeda, Clara Oliva, Jordi Garcia-Fernàndez, Rafael Artuch, Francesc Villarroya, Gemma Marfany
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Neurobiology of Disease
Subjects:
Retinal dystrophies
Retinitis pigmentosa
CERKL
Mitochondrial dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001546

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http://www.sciencedirect.com/science/article/pii/S0969996121001546

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