Asthmatic Airway Vagal Hypertonia Involves Chloride Dyshomeostasis of Preganglionic Neurons in Rats

Asthmatic Airway Vagal Hypertonia Involves Chloride Dyshomeostasis of Preganglionic Neurons in Rats

Airway vagal hypertonia is closely related to the severity of asthma; however, the mechanisms of its genesis are unclear. This study aims to prove that asthmatic airway vagal hypertonia involves neuronal Cl– dyshomeostasis. The experimental airway allergy model was prepared with ovalbumin in male ad...

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Bibliographic Details
Main Authors: Ding He, Hong Chen, Ming Zeng, Chunmei Xia, Jin Wang, Linlin Shen, Danian Zhu, Yonghua Chen, Jijiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
Subjects:
Na+-K+-2Cl– co-transporter 1/K+-Cl– co-transporter 2
asthma
microglia
bumetanide
airway vagal preganglionic neuron
minocycline
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00031/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00031/full

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