Tristetraprolin Posttranscriptionally Downregulates TRAIL Death Receptors

Tristetraprolin Posttranscriptionally Downregulates TRAIL Death Receptors

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) has attracted attention as a potential candidate for cancer therapy. However, many primary cancers are resistant to TRAIL, even when combined with standard chemotherapy. The mechanism of TRAIL resistance in cancer cells has not be...

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Bibliographic Details
Main Authors: Won Hyeok Lee, Myung Woul Han, Song Hee Kim, Daseul Seong, Jae Hee An, Hyo Won Chang, Sang Yoon Kim, Seong Who Kim, Jong Cheol Lee
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
tumor necrosis factor-related apoptosis-inducing ligand
death receptor
tristetraprolin
posttranscriptional modification
AU-rich elements
cancer treatment
Online Access:https://www.mdpi.com/2073-4409/9/8/1851

Internet

https://www.mdpi.com/2073-4409/9/8/1851

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