Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone

Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone

The LβT2 mouse pituitary cell line has many characteristics of a mature gonadotrope and is a widely used model system for studying the developmental processes and the response to gonadotropin-releasing hormone (GnRH). The global epigenetic landscape, which contributes to cell-specific gene regulator...

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Bibliographic Details
Main Authors: Frederique Ruf-Zamojski, Miguel Fribourg, Yongchao Ge, Venugopalan Nair, Hanna Pincas, Elena Zaslavsky, German Nudelman, Stephanie J. Tuminello, Hideo Watanabe, Judith L. Turgeon, Stuart C. Sealfon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Endocrinology
Subjects:
LβT2
gonadotrope
gonadotropin-releasing hormone
chromatin accessibility mapping
transcription profiling
single-cell transcriptomics
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00034/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00034/full

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