Molecular classification of nemaline myopathies: “nontyping” specimens exhibit unique patterns of gene expression

Molecular classification of nemaline myopathies: “nontyping” specimens exhibit unique patterns of gene expression

Nemaline myopathy (NM) is a slowly progressive or nonprogressive neuromuscular disorder caused by mutations in genes encoding skeletal muscle sarcomeric thin filament proteins. It is characterized by great heterogeneity at the clinical, histopathological, and genetic level. Although multiple molecul...

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Bibliographic Details
Main Authors: Despina Sanoudou, Leslie A. Frieden, Judith N. Haslett, Alvin T. Kho, Steven A. Greenberg, Isaac S. Kohane, Louis M. Kunkel, Alan H. Beggs
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Neurobiology of Disease
Subjects:
Microarrays
Nemaline myopathy
Gene expression
Troponin T
Skeletal muscle
Neuromuscular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104000038

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http://www.sciencedirect.com/science/article/pii/S0969996104000038

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