Inter- and intra-host viral diversity in a large seasonal DENV2 outbreak.

High genetic diversity at both inter- and intra-host level are hallmarks of RNA viruses due to the error-prone nature of their genome replication. Several groups have evaluated the extent of viral variability using different RNA virus deep sequencing methods. Although much of this effort has been de...

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Bibliographic Details
Main Authors: Camila Malta Romano, Michael Lauck, Felipe S Salvador, Célia Rodrigues Lima, Lucy S Villas-Boas, Evaldo Stanislau A Araújo, José Eduardo Levi, Claudio Sergio Pannuti, David O'Connor, Esper Georges Kallas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732279?pdf=render