Adenosine A(2A) receptors measured with [C]TMSX PET in the striata of Parkinson's disease patients.

Adenosine A(2A) receptors (A2ARs) are thought to interact negatively with the dopamine D(2) receptor (D2R), so selective A2AR antagonists have attracted attention as novel treatments for Parkinson's disease (PD). However, no information about the receptor in living patients with PD is available...

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Main Authors: Masahiro Mishina, Kiichi Ishiwata, Mika Naganawa, Yuichi Kimura, Shin Kitamura, Masahiko Suzuki, Masaya Hashimoto, Kenji Ishibashi, Keiichi Oda, Muneyuki Sakata, Makoto Hamamoto, Shiro Kobayashi, Yasuo Katayama, Kenji Ishii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046146?pdf=render