The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA

Many cellular constituents travel along microtubules in association with multiple copies of motor proteins. How the activity of these motors is regulated during cargo sorting is poorly understood. In this study, we address this issue using a novel in vitro assay for the motility of localising Drosop...

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Bibliographic Details
Main Authors: Harish Chandra Soundararajan, Simon L Bullock
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01596