The measurement of lysosomal phospholipase A2 activity in plasma

The measurement of lysosomal phospholipase A2 activity in plasma

A deficiency of lysosomal phospholipase A2 (LPLA2) causes macrophage-associated phospholipidosis, suggesting that the enzyme is important in the lipid catabolism. Because LPLA2 is secreted by macrophages, extracellular LPLA2 activity may potentially reflect a change in macrophage activation. In this...

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Bibliographic Details
Main Authors: Akira Abe, Robert Kelly, James A. Shayman
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Journal of Lipid Research
Subjects:
lysosomal phospholipase A2-knockout mouse
group XV phospholipase A2
serum
dioleoylphosphatidylglycerol
N-acetylsphingosine
1-O-acyl-N-acetylsphingosine
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752037084X

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http://www.sciencedirect.com/science/article/pii/S002222752037084X

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