Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture.

Correlative analysis of molecular markers with phenotypic signatures is the simplest model for hypothesis generation. In this paper, a panel of 24 breast cell lines was grown in 3D culture, their morphology was imaged through phase contrast microscopy, and computational methods were developed to seg...

Full description

Bibliographic Details
Main Authors: Ju Han, Hang Chang, Orsi Giricz, Genee Y Lee, Frederick L Baehner, Joe W Gray, Mina J Bissell, Paraic A Kenny, Bahram Parvin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2829039?pdf=render