The Antiproliferative and Apoptotic Effect of a Novel Synthesized <i>S</i>-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos

The Antiproliferative and Apoptotic Effect of a Novel Synthesized <i>S</i>-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos

Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties were prepared using <i>s-</i>triazine as a scaffold. These compounds were evaluated for their anticancer activity against two human breast cancer cell lines (MCF-7 and MDA-MB-231), a colon...

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Bibliographic Details
Main Authors: Azizah M. Malebari, Rakia Abd Alhameed, Zainab Almarhoon, Muhammad Farooq, Mohammad A. M. Wadaan, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
s-triazine
dipeptides
anti-proliferative activity
apoptosis
zebrafish
Online Access:https://www.mdpi.com/1420-3049/26/4/1170

Internet

https://www.mdpi.com/1420-3049/26/4/1170

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