Proteomic Profiling of Tissue Exosomes Indicates Continuous Release of Malignant Exosomes in Urinary Bladder Cancer Patients, Even with Pathologically Undetectable Tumour

Proteomic Profiling of Tissue Exosomes Indicates Continuous Release of Malignant Exosomes in Urinary Bladder Cancer Patients, Even with Pathologically Undetectable Tumour

Invasive urothelial bladder cancer (UBC) has high recurrence rates even after radical cystectomy (RC). Exosomes are membrane-bound nanovesicles, which have been shown to contribute to carcinogenesis and metastasis. We previously showed that urinary exosomes display a malignant profile in UBC patient...

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Bibliographic Details
Main Authors: Maria Eldh, Michael Mints, Stefanie Hiltbrunner, Sam Ladjevardi, Farhood Alamdari, Markus Johansson, Tomasz Jakubczyk, Rosanne E. Veerman, Ola Winqvist, Amir Sherif, Susanne Gabrielsson
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
extracellular vesicles
exosomes
urinary bladder neoplasms
neoadjuvant therapy
cystectomy
proteomics
Online Access:https://www.mdpi.com/2072-6694/13/13/3242

Internet

https://www.mdpi.com/2072-6694/13/13/3242

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