Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis

The spread of multidrug-resistant microorganisms globally has created an urgent need for novel therapeutic strategies to combat urinary tract infections (UTIs). Immunomodulatory therapy may provide benefit, as treatment of mice with dexamethasone during acute UTI improved outcome by reducing the dev...

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Bibliographic Details
Main Authors: Thomas J. Hannan, Pacita L. Roberts, Terrence E. Riehl, Sjoerd van der Post, Jana M. Binkley, Drew J. Schwartz, Hiroyuki Miyoshi, Matthias Mack, Reto A. Schwendener, Thomas M. Hooton, Thaddeus S. Stappenbeck, Gunnar C. Hansson, William F. Stenson, Marco Colonna, Ann E. Stapleton, Scott J. Hultgren
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:EBioMedicine
Subjects:
Immunomodulatory therapy
Mucosal immunology
Immunopathology
Uropathogenic E. coli
UPEC
COX-2
Urinary tract infection
UTI, recurrent infection
Chronic infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396414000139

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http://www.sciencedirect.com/science/article/pii/S2352396414000139

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