Evaluation of a FRET-peptide substrate to predict virulence in Pseudomonas aeruginosa.

Pseudomonas aeruginosa produces a number of proteases that are associated with virulence and disease progression. A substrate able to detect P. aeruginosa-specific proteolytic activity could help to rapidly alert clinicians to the virulence potential of individual P. aeruginosa strains. For this pur...

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Bibliographic Details
Main Authors: Wendy E Kaman, Nora El Arkoubi-El Arkoubi, Sanne Roffel, Hubert P Endtz, Alex van Belkum, Floris J Bikker, John P Hays
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3841150?pdf=render