Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus.

Newborn granule cells become functionally integrated into the synaptic circuitry of the adult dentate gyrus after a morphological and electrophysiological maturation process. The molecular mechanisms by which immature neurons and the neurites extending from them find their appropriate position and t...

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Bibliographic Details
Main Authors: Sebastian Jessberger, Stefan Aigner, Gregory D Clemenson, Nicolas Toni, D Chichung Lie, Ozlem Karalay, Rupert Overall, Gerd Kempermann, Fred H Gage
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18998770/pdf/?tool=EBI