Causalcall: Nanopore Basecalling Using a Temporal Convolutional Network

Nanopore sequencing is promising because of its long read length and high speed. During sequencing, a strand of DNA/RNA passes through a biological nanopore, which causes the current in the pore to fluctuate. During basecalling, context-dependent current measurements are translated into the base seq...

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Bibliographic Details
Main Authors: Jingwen Zeng, Hongmin Cai, Hong Peng, Haiyan Wang, Yue Zhang, Tatsuya Akutsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01332/full