Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I

Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I

The transport of HDL cholesteryl esters (CE) from plasma to the liver involves a direct uptake pathway, mediated by hepatic scavenger receptor B-I (SR-BI), and an indirect pathway, involving the exchange of HDL CE for triglycerides (TG) of TG-rich lipoproteins by cholesteryl ester transfer protein (...

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Bibliographic Details
Main Authors: Xavier Collet, Alan R. Tall, Humaira Serajuddin, Karim Guendouzi, Lori Royer, Helena Oliveira, Ronald Barbaras, Xian-cheng Jiang, Omar L. Francone
Format: Article
Language:English
Published: Elsevier 1999-07-01
Series:Journal of Lipid Research
Subjects:
HDL-cholesterol
transgenic mice
reverse cholesterol transport
cholesterol metabolism
carrier proteins
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334805

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520334805

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