Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies

Chronic kidney disease (CKD) is an increasing major public health problem worldwide. And CKD shares numerous phenotypic similarities with kidney as well as systemic ageing. Cellular senescence is mainly characterized by a stable cell cycle arrest, senescence-associated secretory phenotype (SASP) and...

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Bibliographic Details
Main Authors: Yao Wang, Ying Wang, Ming Yang, Xingjie Ma
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313846