TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder

TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder

Activation of TRP channels expressed in urinary bladder afferent nerves and urothelium releases neurotransmitters that influence bladder function. Experiments were undertaken to examine the mechanisms underlying effects of TRPA1 (allyl isothiocyanate, AITC), TRPV1 (capsaicin, CAPS), and TRPC (oleoyl...

Full description

Bibliographic Details
Main Authors: Stephanie L. Daugherty, Jonathan M. Beckel, Kyoungeun A. Kim, Bruce A. Freeman, Jiaxin Liu, Shaoyong Wang, William C. de Groat, Xiulin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
nitro-oleic acid
afferent nerves
TRP channels
guinea pig
urinary bladder
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.692719/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.692719/full

Similar Items