Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships

<p>Abstract</p> <p>Background</p> <p>The neprilysin (M13) family of endopeptidases are zinc-metalloenzymes, the majority of which are type II integral membrane proteins. The best characterised of this family is neprilysin, which has important roles in inactivating signa...

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Bibliographic Details
Main Authors: Pinney John W, Bland Nicholas D, Thomas Josie E, Turner Anthony J, Isaac R Elwyn
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/8/16