Phosphorylation Modulates the Subcellular Localization of SOX11

Phosphorylation Modulates the Subcellular Localization of SOX11

SOX11 is a key Transcription Factor (TF) in the regulation of embryonic and adult neurogenesis, whose mutation has recently been linked to an intellectual disability syndrome in humans. SOX11’s transient activity during neurogenesis is critical to ensure the precise execution of the neurogenic progr...

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Bibliographic Details
Main Authors: Elli-Anna Balta, Marie-Theres Wittmann, Matthias Jung, Elisabeth Sock, Benjamin Martin Haeberle, Birgit Heim, Felix von Zweydorf, Jana Heppt, Julia von Wittgenstein, Christian Johannes Gloeckner, Dieter Chichung Lie
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
SOX11
transcription factor phosphorylation
subcellular localization
neurogenesis
cancer
intellectual disability
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00211/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00211/full

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